Individuals with these mutations typically have familial hypercholesterolemia.
These genes provide information for the formation of the low-density lipoprotein receptor, a receptor that binds to low-density lipoproteins (LDLs). LDLs carry the cholesterol in the blood and regulate the amount of cholesterol in the circulation. Mutations to these genes either reduce the number of receptors or cause several disruptions to their function. This results in high blood cholesterol levels and in a higher risk for heart disease.
The answer is endocytosis
It allows scientists to explore new explanations for observations.
Answer:
It is fascinating to observe two distinct characters presented by the same plant. The inheritance of this plant can be determined easily by crossing the pure violets exhibiting yellow petals with dark brown marking and erect stems with violets exhibiting no markings, white petals, and prostate stems.
The F1 progeny will originate as a hybrid of the two characters. These F1 plants will then be crossed between themselves and the F2 progeny would be clearly evaluated. If the F2 plants come in the phenotypic ratio of 3: 1, then it would indicate the pleiotropic effect of the alleles found in a single locus. If any other combinations arise post crossing, it would indicate that the non-wild type phenotype is because of many distinct mutant genes.
