Question

Indicate whether the following statements are true or false. If a statement is false, explain why it is false. A. Generally, the total number of nonpolar amino acids has a greater effect on protein structure than the exact order of amino acids in a polypeptide chain. B. The "polypeptide backbone" refers to all atoms in a polypeptide chain, except for those that form the peptide bonds. C. The chemical properties of amino acid side chains include charged, uncharged polar, and nonpolar. D. The relative distribution of polar and nonpolar amino acids in a folded protein is determined largely by hydrophobic interactions, which favor the clustering of nonpolar side chains in the interior.

Answer 1

A. False. The order in which amino acids are linked is unique for each protein and isthe most important factor in determining overall protein structure.

B. False. Peptide bonds are planar amide bonds that are central to the polypeptide

backbone formation. The atoms in the amino acid side chains are not considered

to be part of the backbone.

C. True.

D. True.