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Kryger [21]
3 years ago
15

Based on your phylogenetic tree, how many times—at a minimum—do you infer that an HIV virus has jumped hosts to humans?

Biology
1 answer:
Molodets [167]3 years ago
8 0
<h2>Phylogeny and virus</h2>

Explanation:

Human immune deficiency virus forms the major cause of AIDS(Acquired immune deficiency syndrome)

  • Phylogenetic analyses have showed that chimpanzees were the original hosts for this class of viruses
  • Four lineages of HIV have arisen due to the independent cross species transmission to humans and two of these transmissions may have been through gorillas
  • Simian immunodeficiency viruses(SIV) are the closest relatives of HIV infecting wild type chimpanzees and gorillas in west central Africa
  • 98% of HIV infections are caused by HIV-1 group M,the virus has a fast rate of evolution and must have circulated within the population of humans for many years
  • First species found to be infected naturally were African green monkeys where prevalence of infection is high
  • HIV-1 and HIV-2 form a distinct clade within the lentiviruses indicating that humans have acquired  their infections from other primates
  • Sooty mangabeys(monkey) in West Africa ere the source of HIV-2 strains and there must have been multiple mangabey to human cross species jump
  • A virus related to HIV-1 was reported in the year 1989 and was found in two captive chimpanzees in Gabon
  • In 1999 a example of SIV was found from a chimpanzee
  • Transmission from chimpanzee to humans gave rise to M and N groups which probably occurred in the locations where closely related SIV strains were found
  • Most SIV's infect monkey species whereas chimpanzees(like humans)are apes,it is observed that chimpanzees initially acquired SIV's from monkeys
  • The opportunities for chimpanzee-or monkey-to-human host jumps have existed for hundreds or thousands of years and it is expected that such transmissions might have occurred in the past
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