Conjunctive adverbs connect one clause to another clause, or one idea to another idea:
Joanne was very good at math; however, she is not good at English.
Descriptive adjectives can be separated with commas in a sentence such as:
Joanne did not want to pet the smelly, wet dog.
that WITCH really is evil lol
There were patches of blue sky showing here and there through the clouds that had met and piled one above the other in the west facing her window.