<span>Assuming that this is referring to the same list of options that was posted before with this question, the most likely theme would be "creative" since this is the modern trend. </span>
The answer is the difficulty of determining what is real. Typical modernists had a loss of meaning in the modern world, so there themes included the question of "What is real?" There was a search for meaning in a world without God, and a search for self with a critique of traditional values.
I believe (B) is the best answer here. Chief Seattle is saying that they would lose everything and gain nothing and thus it would be foolish (be in vain) to battle the white man.
