Answer:
Antibiotic resistance is when pathogens such as bacteria or fungi develop a resistance to antibiotics. This happens when some pathogens die, and others survive. The small number of pathogens that had a resistance to the antibiotic will reproduce more offspring that are also resistant to, and those offspring will reproduce even more offspring and so on. Eventually most pathogens will be resistant to the antibiotic, so antibiotics won't work.
The answer is A, denature.
As each type of enzymes has its own optimum temperature, like the temperature that they work fastest at, so if the temperature goes too high above the optimum, the 3D structure of the enzyme breaks apart and deforms and they can no longer bind with substrates thus no longer works. In this scenario, we say the enzyme is denatured.
Note that only if the temperature is too high can make the enzyme denature, if the temperature is too low, instead, the enzyme would be inactive, but once the temperature goes back to normal, they work again. Unlike denatured enzymes, which does not work even if the temperature goes back to normal.
Like 50 miles for the outermost layer which is called the LITHOSPHERE
We see that this is a region near the continents, so it is probable that there is the boundary of a tectonic plates around there. Since there are islands there, it is quite probable that there is a subduction zone near them which means that the oceanic crust is going below the continental one and the continental is slowly elevated. This also shows that the boundary is convergent, since transform boundaries do not lead to elevation. Near convergent boundaries, there are frequently volcanoes and shallow earthquakes. Finally, the climate near Alaska is cold and this does not depend on whether islands are near a boundary or not. So, 2 4 and 5 are correct.