Answer:
Catastrophe
Explanation:
Analogies are fun. In this one, difference is to opposite as catastrophe is to disaster. Difference and opposite are synonyms, so the blank is a synonym.
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A suffix ment of nouns, often concrete, denoting an action or resulting state ( abridgment; refreshment), a product ( fragment), or means ( ornament)
Suffix -tion. (non-productive) Used to form nouns meaning "the action of (a verb)" or "the result of (a verb)". Words ending in this suffix are almost always derived from a similar Latin word; a few (eg gumption) are not derived from Latin and are unrelated to any verb.
