Answer:
In this study, we tested the effects of NEAA-deprived diets and checkpoint inhibitor anti-PD-1 and anti-PD-L1 in colon cancer using syngeneic mouse model (Balb/c) bearing tumors of mouse colorectal cancer cell line CT-26. Three diets were tested, including a natural rodent diet Teklad ENVIGO Global 16% Protein Rodent Diet (control 1), a formulated NEAA-complete diet COMPLETE (control 2, using amino acid mix in place of protein), and a formulated NEAA-deprived diet FTN203 (treatment, using amino acid mix in place of protein). Both COMPLETE and FTN203 have the same nutritional structures, contain 17% w/w protein equivalent, and are isocaloric. After tumor size-based randomization, these diets were provided to mice ad libitum throughout the whole test. Each of these diets was used alone or combined with anti-PD-1 antibody (i.p., twice per week for 2 weeks) or anti-PD-L1 antibody (i.v., twice per week for 2 weeks).
Explanation:
1938 hitler demanded self-determination for all Germans in Austria
Answer with Explanation:
<em>Genetics' influence on the happiness</em> of a person has long been studied. Some people say that the genes of a person affects the person's mood. For example, "5-HTTLPR" is a gene that is regarded to be connected to depression. This is why it is called<u> "the depression gene."</u> It is also associated with sleep disorders like "insomnia." When someone has trouble sleeping, it disrupts his way of life thereby affecting his happiness.
On the contrary, the genes exhibit themselves according to external environments. This is also one reason why a person's happiness may also be determined by his<em> success in life, material possession, relationships with people and so on.</em> So, a person's situation in life partly influences his happiness.
