Answer:
using multiple origins of replication on each chromosome
Explanation:
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The mantle being made of nickel and iron is the correct statement about the geosphere and is denoted as option B.
<h3>What is Geosphere?</h3>
This is referred to the solid part of the earth and consists of rocky materials present in it.
The geosphere has the mantle which is made up of materials such as iron and nickel which are metals and are responsible for their rigid solid structure thereby ,making it the most appropriate choice.
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Answer:
Methotrexate inhibits the synthesis of DNA, RNA, and protein synthesis of the cells in the experiment.
Explanation:
Methotrexate competitively inhibits the enzyme dihydrofolate reductase (DHFR) which is involved in the synthesis of tetrahydrofolate from the inactive dihydrofolate. The methotrexate blocks the enzyme by binding to its active site thereby preventing further reaction of the dihydrofolate reductase enzyme and dihydrofolate. Tetrahydrofolate is a useful material for the de novo synthesis of thymidine, a nucleoside. And without thymidine, DNA synthesis is hindered. Methotrexate therefore inhibits the synthesis of DNA, RNA, thymidylates and of course protein synthesis.