Not clear on your question here.. but substance abuse is when you abuse a substance and usually an illegal one such as drugs or alcohol, and when you increase that, you're just using it more? I want to help you but the question is unclear to me!
Answer:
The war of 1812 resulted in peace for two centuries.
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During this period, many European nations were in constant conflict with each other as they struggled to increase their power and wealth. Many of these nations believed trade with other countries was the best way to increase wealth. ... As a result, European leaders began to seek new sea routes to Asia.
The ultimate colonial objection to the Sugar Act was that it was taxation without representation. The colonists were being taxed from Great Britain without someone representing their rights and ideas in Parliament in London. They were also unfairly being taxed to bring more money into the colonial superpower, instead of it being used for the Thirteen Colonies.
It could be either A or D, but I due to the lack of third party votes they're not really counted in elections, so answer D.