I believe this question is trying to get you to realize the difference between acquired traits(one you get through doing something during life) and heritable traits(ones from Mom/Dad). For example, I really wish I was 6 foot 4... but the height trait comes genetically from your parents since it is coded in my DNA how tall I will be, therefore this trait must be passed down genetically and somewhere down the evolutionary tree the humans in the region which my family comes from was better off being short. An example that comes from acquired traits could be muscularity... my parents are both not very muscular but throughout my lifetime I enjoy working out and have become much more muscular, no matter how much your parents or grandparents lift weights YOU won't change so that change must be acquired through aging during your lifetime. Now the amount of muscle your body can put on is a heritable thing but that is beside the point. Hope this helps :)
The Human Genome Project. The project was a international scientific research project with the goal determining the sequence of nucleotide base pairs that make up human DNA.
Answer:
The correct answer is "Histones in general have a net negative charge that allow them to bind to DNA. Acetylation of histones, decreases their positive charge and weakens the histone-DNA interaction".
Explanation:
Histone acetyltransferases (HATs) are regulators of gene activation and deactivation, achieved by the transference of an acetyl group from acetyl-CoA to histones. HATs function by the premise that histones in general have a net negative charge that allow them to bind to DNA. Acetylation of histones, decreases their positive charge and weakens the histone-DNA interaction. Therefore, most of the times histone acetylation increases gene expression, because the acetylated gene is free from the histones and is able to be encoded.