Both bacteria and archaea have different Ribosomal RNAs. These two microorganisms also differ in genetic and biochemical ways.
Archaea: cell membrane contains ether linkages; cell wall lacks peptidoglycan; genes and enzymes behave more like Eukaryotes; have three RNA polymerases like eukaryotes; and extremophiles
Bacteria: cell membrane contains ester bonds; cell wall made of peptidoglycan; have only one RNA polymerase; react to antibiotics in a different way than archea do.
1. Bacteria cannot live above 100 degrees Celsius; archaea can thrive in extreme temperatures. Archaea are actually extremophiles. They can survive in extreme physical and geochemical conditions.
2. Bacterial cell walls have peptidoglycan (mesh-like structure also known as murein); archaeal cell walls do not have peptidoglycan.
