* More than 40 proteins and glycoproteins involved in the complement system are synthesized by the liver, macrophages, epithelial cells, they are present in the blood in plasmatic form, membrane, some have an enzymatic activity, regulator or membrane receptorThese are elements of the humoral innate immune response, they fight infections, purify immune complexes and apoptotic bodies.
<span>There are indeed three ways to activate the complement:</span>
Classical pathway: Activated by Immunoglobulins in immune complexes, aggregated Immunoglobulins, DNA, CRP, apoptotic bodies .......it involves nine fractions, starting with C1, then C4, C2, C3, to form a classical C5 convertase, then, activation of C5, C6, C7, C8, C9.
Alternative pathway: activated by polysaccharides (bacterial endotoxin), vascular wall poor in sialic acid, aggregated IgE ...C3b like is the first component in the alternate channel cascade, it will create an amplification loop, and form an alternative C5 convertase.
Lecithin pathway: Activated by mannose, fucose (carbohydrate of microorganisms)The first component is the complex MBL / MASP1 / MASP2: "mannose-binding protein": works according to the same principle as the complex C1 of the classical way (MASP2 cleaves the C4 and the rest of the cascade is equivalent to that of the classical way).
the three ways have the same outcome: A C5 convertase (formed by one of the pathways) cleaves C5 into C5a and C5b: C5b is deposited far from other fractions on the antigenic surface. The fixation of C5b in the cell is followed by that of C6, C7, C8, and C9 (9 molecules of C9): formation of the membrane attack complex (MAC) ==> Death of the cell by osmotic shock
The four main stages of Interphase are Gap 0, Gap 1, S phase and Gap 2. Interphase appears to be a resting stage in cell divisions but actually many activities or processes happens at this phase. Interphase generally lasts at least 12 to 24 hours in mammalian tissue.
The two contrasts between seagulls and wild geese are migration and their sizes. One way they are similar is that they can both fly for great distances. The other way is that they are similar is that are both very large in size. The correct answer is A.
Answer:
Seeds are the result of plant reproduction. ... When pollen lands on the flower's stigma, it germinates and forms a pollen tube, which then quickly grows towards the plant's ovary. Once it finds an ovule, the pollen tube bursts to release sperm cells, which fertilize the ovule and initiate seed formation.
Explanation:
Answer:
Sexual reproduction involves the fusion of male and female gametes to form a zygote. The fusion of the nuclei of male and female gametes is known as fertilization. Asexual reproduction does not involve gametes, instead parts of a mature organism may develop to new individuals
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