He discouraged vaccinations because disease was a natural means of population control.
Thomas Malthus worried that the amount of resources ( such as food and water) in the world would not be able to keep up with the increasing number of population in the world.
He believed that diseases are natures'ways of population control to ensure that the resources is enough to accommodate all organisms in the world. Because of this, he believe vaccinations as interference of the natural order.
The ideas brought by Christian Missionaries influenced the religion, government, and education of many West African societies.
The right answer is B. The Catholic Monarchs supported Columbus in his project to reach Asia, allowing him to make four trips (in 1492, 1493, 1498 and 1502). In the first one of them he arrived not to India (as he expected) but to the island of Guanahani, in the Bahamas. In addition, they granted him a certain number of privileges, such as the title of Admiral, Governor and Viceroy of the Indies, and a percentage of the riches he found.