Answer:
a. It is a competitive inhibitor.
Explanation:
A competitive inhibitor competes with the substrate for the active site of the enzyme. Binding of the competitive inhibitor to the active site of enzyme forms enzyme-inhibitor complex and does not allow the substrate to bind to the enzyme. This inhibits the reaction. However, the competitive inhibition is overcome by increasing the concentration of substrate around the enzyme to facilitate its binding to the enzyme's active site.
According to the given information, malonic acid competes with succinate for the active site of enzyme succinate dehydrogenase and inhibits the reaction. This inhibition is overcome by increasing the succinate concentration around the enzyme. This makes malonic acid a competitive inhibitor to succinate dehydrogenase.
<h3><em><u>C.</u></em><em><u> </u></em><em><u>This cell has no nucleus.</u></em></h3>
Because bacterial cell do not have a well-defined nuclear membrane. The coiled DNA particles lie naked in the cytoplasm. This is called nucleoid. While in animal cells the nucleus is surrounded by a well-defined nuclear membrane.
Answer:
Penicillin:
Staphylococcus epidermidis is more sensitive to Penicillin as compared to E. coli
Novobiocin:
Staphylococcus epidermidis is more sensitive to Novobiocin as compared to E. coli.
Gentamicin:
E. coli isolates showed high rates of resistance to gentamicin as compared to Staphylococcus epidermidis
Explanation:
Kirby-Bauer diffusion test:
This test is also known as disk diffusion antibiotic sensitivity testing. This test uses antibiotic containing disks to test its inhibition against particular bacteria.
Staphylococcus epidermidis:
Gram-positive bacterium, which is part of the normal human flora and found mostly in skin flora but less commonly in mucosal flora.
E. coli
Gram-negative bacteria because its cell wall have an additional layer. During the staining process, it stains negative as compared to gram positive bacteria.
Penicillin:
This antibiotic kills bacteria by inhibiting the final step in cell wall biosynthesis, hence penicillin is most effective against gram-positive bacteria. Hence Staphylococcus epidermidis is more sensitive to Penicillin as compared to E. coli
Novobiocin:
Antibiotics which inhibits bacterial DNA synthesis. Its targets are the bacterial DNA gyrase and associated enzyme DNA topoisomerase. Due to extra membrane present outside gram negative bacteria this antibiotic is less effective against E. coli. Hence Staphylococcus epidermidis is more sensitive to Novobiocin as compared to E. coli.
Gentamicin:
Gentamicin is the broad spectrum antibiotic Its mode of action involves bacterial protein synthesis inhibition by binding to 30S ribosomes. E. coli isolates showed high rates of resistance to gentamicin as compared to Staphylococcus epidermidis
Answer:
D
Explanation:
it gives off energy as a product