Answer: GMO crops have significantly increased crop yields and simultaneously decreased pesticide use. By doing these two things combined, we are producing more food with less inputs. ... Genetic characteristics in fruits and vegetables, such as insect- and disease-resistance, can also help farmers use less pesticides.
I don't know whether this is the best way of phrasing it , but the statement is true.
North Korea is a dictatorship, and the government is not allowing medical aid from abroad because they don't want to loose their control of the territory.
They also don't use the methods of farming found in other places and which proved to be more efficient.
A antonym for biosphere is an environment that is not natural.
I believe it would be Istanbul in Turkey