Mainly because it toughened-up the Fugitive Slave Act, allowing official slave-catchers to hunt down runaways.
This recruited many new Abolitionists, and caused Harriet Beecher Stowe to write 'Uncle Tom's Cabin'.
In 1794 an uprising of farmers and distillers in Pennsylvania became known as the Whiskey Rebellion
D. Because France and England had major beef so they took their land as an "in your face France."