Paliperidone has low affinity
for lipid-rich environments compared from the parent compound risperidone. Due to
its hydrophilicity characteristic, paliperidone is capable of hydrogen bonding
with other molecules containing water and hydroxyl groups. Lipophilicity is a
determining factor for the rate and degree of metabolism of the drug in the
body and for crossing the blood–brain barrier (BBB).
Moreover, these differences are
implicated in synaptic plasticity and neuronal firing effects in the mechanism
of mitochondrial movement, protein expression, and phosphorylation of the drug.
Paliperidone as a mood stabilizer is an active metabolite of risperidone with antipsychotic effects used
for the treatment of schizophrenia and its associated disorders.
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Answer:
The plus end for all actin filaments.(Ans. A)
Explanation:
All three types of muscles (cardiac, smooth, and skeletal) utilize actin filaments to generate force which leads to cell contraction. Actin filaments is organized into sarcomeres which function as the fundamental unit of contraction.
Sarcomeres are approx 2.4 micro meter in length, and they are bounded at both end with the help of Z-disks. Plus end of the Z-disks are oriented with actin filaments and their minus ends to the direction of center of the sarcomeres. Z-disk consist an actin capping protein, which is known as cap-Z. Cap-Z helps to bind plus end of the actin filaments.
I believe lactic acid fermentation is used for all three!
Answer:
C
Explanation:
Interphase is the uniform phase for all cells division'. It signifies the begin of any cell cycle division. it is the period of prolong rest by the cells to prepare for the long journey of cell division. It involved replication of DNA, of organelles to be distributed in the daughter cells, accumulation of food resources .,
It is made up of the G1, for normal growth of cells and function of cells, doubling of organelles numbers.
S=synthesis stage, for DNA and genetic material replications
and the G2 phase growth resumption and preparation of cells division.
Therefore since all cells must undergo Interphase and carry out all the above processes prior to cell division, this stage(interphase) must be uniform to all cells.
Answer: Option (A) is the correct answer.
Explanation:
It is given that the unknown substance is solid at 15 degree celsius. When further heated then heat energy breaks the bond between molecules of the solid.
As a result, temperature remains constant until all the bonds are broken down to convert the solid into liquid.
Hence, the constant 17 degree celsius temperature shows that the solid is melting and after it completely melts then it converts into liquid at 23 degree celsius.
Thus, we can conclude that the statement its melting point is 17 °C, is correct about the unknown substance.
