The south— the north (mostly) opposed slavery, whereas the south (mostly) wanted to keep it around. In fact, slavery was one of the main reasons the American Civil War was fought in the first place.
I know that manifest destiny was the mindset of Americans that they were destined to stretch from coast to coast.
The Louisiana purchase was during that time. Napoleon didn't have the troops to keep Louisiana so he sold it to us for cheap.
Less based around slavery
The largest numbers of Loyalists were in the middle colonies (New York, New Jersey and Pennsylvania).
