Artificial selection is done either by inbreeding or cross breeding. Inbreeding is the crossing of genetically closely related individuals and is useful for retaining desirable qualities. Hybrids are formed from artificial selection. Hybridization results when varieties of organisms with different characteristics are crossed. The resulting offspring often show characteristics which are superior to either of the parents and are said to possess hybrid vigour.
This isn’t B, because it’s only one species. It isn’t C, because it is one population, and A doesn’t make sense due to how they are of course organisms. D is your best bet.