Question

Mi abuela _____ muy inteligente. También _____ guapa. A. está / es B. es / es C. es / está D. está / está

Answer 1

Mi abuela es muy inteligente. También guapa
My grandmother is very intelligent and she is beautiful too

Answer 2

The answer is B.  "Esta" is more of a location  and feeling word and "es" is a description word.  The phrases are talking about how she is smart and pretty so they are both describing her therefor he answer is B.