Answer:
Most were located in the Northeast because merchants there had money to invest in new mills. Also, this region had many rivers that provided a reliable supply of power. In the South, investors concentrated on expanding agriculture.
The Powhatan natives helped out the colonists of James town, and at first the colonists were grateful, but then it changed because the colonists started to treat the natives like slaves, also in 1609, 400 more settlers came to Jamestown, as a response the natives attacked the colonists.