Question

How are autosomal dominant disorders different from autosomal recessive disorders?

Answer 1

Answer:

Answered below

Explanation:

An autosome is defined as a non-sex chromosome. They are made up of chromosomes from 1 to 22. An autosomal disorder occurs when there is mutations on one of these chromosomes from 1 to 22.

Inheritance patterns show how disease is being transmitted in families.

In autosomal dominant disorders, there is one copy of mutated gene and one copy of the normal gene on a pair of autosomal chromosomes. The single copy of mutant gene is enough for cause a disease manifestation. Examples of these disorders include; Huntington's disease, polycystic kidney disease and neurofibromatosis.

In autosomal recessive disorders, there must be two copies of the mutant gene to cause a disease. In autosomal recessive disorders, parents are typically, carriers. Examples of these disorders include; sickle cell anemia and cystic fibrosis.

Answer 2

Answer:

Autosomal dominant disorders only require a minimum of one dominant allele in order to be expressed while autosomal recessive disorders require two recessive alleles

Explanation:

Autosomal dominant disorders are different from autosomal recessive disorders due to the fact that the former requires a minimum of one dominant allele in order to express itself while the latter requires that two recessive alleles be present before it can be expressed.

Alleles for autosomal disorders are generally located on autosomes - the non-sex determining chromosomes.

For example, an autosomal dominant disorder's gene represented by the allele A (alternate form, a) will be expressed in an individual with genotype AA or Aa. If the disorder is autosomal recessive, it can only be expressed with the genotype aa.