What I know of Sister Mary Joseph is from a disease. It is a nodule. Anyway, according to context, the best answer would be letter C. The word that best describes Sister Mary Joseph is Spiritual. This is because of the amount of biblical reference from the names.
Old Major's instruction is given in chapter one during the meeting in the old barn. All the animals have assembled to hear what he has to stay. The key point of his directive is that the animals should rise up against Man and be rid of him forever.