I think the answer could be B or D?
North was most responsible for "killing" reconstruction.
In World War II the world lost 50 to 70 million people, mostly Europeans, including millions of Jews, which was nearly 35.3% of the world Jewish population. Between 1935 and 1940, 12 percent of the population moved to another county or state. This represented a lull in population movement that changed during and after WWII as geographic mobility increased in the U.S. For instance, between 1940 and 1947, 21.5 percent of civilians moved to different counties or states.
Biological warfare was effective against the Inca because there immune system's were not used to that type of diseases that Europeans brought over. There are very susceptible to disease and were wiped out quickly