I believe the answer might be D. Hope this helps!!! Sorry if it doesn't!
Affect is to influence something
and
effect for the something that was influenced
affect is something caused like cause and effect but effect is a cause of something
Although Hamlet indicates to the reader that he is not mad, the characters in the play believe that he is. Match the character to his or her reason given for Hamlet's "madness."
1. the death of Hamlet's father
2. the death of Hamlet's father and the ensuing hasty marriage
3. Ophelia's rejection of Hamlet's love
4. disappointment at not being named king after his father's death
Polonius
Rosencrantz and Guildenstern
Claudius
Gertrude