The major way in which border areas of the west were affected by the mixture of people is that a plethora of immigrants from all over the world wanted to expand to the west in order to settle--meaning that people from all backgrounds often fought over land and job opportunities.
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Let's look at the two that you can eliminate without much worry. B and C are not going to say much about ecofriendly technologies.
It's between the New Science Lab and A record of Operational Data. The Operational Data might given you a hint about the need to reduce costs, but it won't say much about how to do it.
I would pick D. The science lab has the best chance of employing alternate ways of looking for cost control using ecofriendly technologies. It is a lab after all, and that is the first place one should seek the most modern ideas.
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Since no attachment is provided, i will try to provide general knowledge on the Bubonic Plague commonly known today as the Black Death which was Pandemic around the World in the mid-13th century, this plague was caused by the yersinia pestis bacteria, which is found among rodent populations and the plague was then spread by fleas that had bitten infected animals which later infect humans or through close proximate with the carriers.The plague was rumor to start from China and it was imported to Europe through Trade via Italy and historians generally estimate the Bubonic Plague killed between 30% and 60% of Europe’s population between 1347 and 1351 which was estimated to be about 25-30 million people