La ciencia es la progresiva aproximación del hombre al mundo real (Max Planck)
Answer:
The given statement is true.
Explanation:
A condition in which uncharacteristically large, unusual and immature RBCs known as megaloblasts gets generated by the bone marrow is known as megaloblastic anemia. The condition can arise due to many causes of which deficiencies of folate or vitamin B12 (cobalamin) are the most general ones. The mentioned vitamins perform an essential function in the generation of RBCs.
The signs and symptoms of megaloblastic anemia are lightheadedness, shortness of breath, pale skin, unusual heartbeat, and dizziness. Some of the other signs of the condition are weakness in muscles, pains and aches, and dyspnea.
Answer:
C. Chemical energy
Explanation:
ATP is an energy-carrying molecule found in the cells of all living things. It captures chemical energy that is obtained from the breakdown of food molecules and releases it to fuel the other cellular processes.
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The function of the nucleolus is: D. Assembly of ribosomes.
The function of the nucleolus is to transcribe DNA into ribosomal RNA and assemble RNA into ribosomal subunits. The creation of RNA is important because RNA makes up ribosomes which are responsible for protein synthesis in the cell.
Answer:
a. p53 activates transcription of WAF1.
Explanation:
<u>WAF1 transcription occurs independent of p53 during oxidative stress so p53 does not play any role in cell cycle arrest in the signaling pathway which involves WAF1 . </u>
In rest of the mentioned options, p53 plays a role directly or indirectly. During double stranded lesion in DNA in G1 phase, a sensor protein known as ATM binds the DNA lesion site. ATM is a serine/threonine kinase which phosphorylates another kinase known as chk2. After phosphorylation,<u> chk2 stabilizes transcription factor p53.</u> p53 further acts as a transcription factor for the synthesis of a protein known as p21 which inhibits G1 phase specific CDK and ultimately cell is arrested in G1 phase. The cell remains in arrested state until the DNA lesion is fully repaired. <u>Hence, p53 indirectly blocks G1 to S transition with the help of p21. </u>
As such <u>WAF1 transcription factor involving pathway</u><u> </u><u>also requires p21 protein for causing cell cycle arrest but in this pathway p21 is not synthesized with the help of p53. </u>
