Question

A population is made up of individuals where 104 have the A1A1 genotype, 55 have the A1A2 genotype, and 37 have the A2A2 genotype. What is the allele frequency of A1? Answer to 2 decimal places.

Answer 1

Answer:

0.67

Explanation:

In this population there are:

• 104 A1A1 individuals
• 55 A1A2 individuals
• 37 A2A2 individuals

N: 196

The frequency of the A1 is the amount of times that allele appears divided by the total number of alleles in the population.

• The A1 allele is present twice in the A1A1 individuals and once in the A1A2.
• Each individual has 2 alleles, so the total number of alleles is N × 2.

The frequency of the A1 allele can be thus calculated using the following formula:

$freq(A1)=\frac{2*A1A1\ + A1A2}{2*N} \\\\freq(A1)=\frac{2*104\ + 55}{2*196} \\\\\\freq(A1)= 0.67$