It's the pull of gravity on an object.
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Areoles are the tissue that make up most of the stem of cacti. These are specialized structure that give birth to flowers and are often tubular and multipetaled. This structure enables the plant to survive in the harsh conditions of the desert and help them absorb water from the soil efficiently.
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End products can either not have an effect on enzymes, as with many biochemical pathways, but can also inhibit enzymes, especially in anabolic pathways (where larger molecules are synthesised from smaller building blocks) to regulate them