Answer:Of Mice and Men teaches a grim lesson about the nature of human existence. Nearly all of the characters, including George, Lennie, Candy, Crooks, and Curley's wife, admit, at one time or another, to having a profound sense of loneliness and isolation.
Explanation: I read the book more than once
A, if the underlined word is handed.
The correct answer among all the other choices is antipodes. This word describes the people who live on opposite sides of the world. Thank you for posting your question. I hope this answer helped you. Let me know if you need more help.