I think it is stage 2
At stage two, the skin breaks open, wears away, or forms an ulcer, which is usually tender and painful. The sore expands into deeper layers of the skin. It may appear as a scrape, blister, or a shallow crater in the skin. At times this stage looks like a blister filled with clear liquid. Also at this stage some skin may be damaged beyond repair or may die.
<h2>Cell Cycle
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Explanation:
Eukaryotes grow and divide by cell cycle.
The main parts of a cell cycle are an ordered series of events – Gap 1 or G1 phase, Synthesis or S phase, Gap 2 or G2 phase, and the mitosis or M phases.
Interphase period (G1, S, G2 phases) - cell grows by size, duplicates its content, replicates its DNA, and finally prepares for mitotic cell division
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Mitosis and cytokinesis - formation of two identical daughter cells
Cell cycle is regulated by regulatory or restrictive checkpoints in the cell cycle which are activated with detection of a defective DNA.
Proliferation of undesired or cells with defective DNA like in case of tumor cells is controlled by the action of suppressing agents like p53 and cyclins.
The tumor suppressor gene protein p53 prohibits division of tumor cells. Cyclins regulate cell cycle by activation of the enzyme cyclin-dependent kinase.
Answer: When the oxygen-rich blood gets to the cells, the cells receive the oxygen and release the carbon dioxide. The blood with less oxygen and a lot of carbon dioxide returns to the heart. Then the heart returns this blood to the lungs where carbon dioxide is released and oxygen is received.
Explanation:
The synthesis of diphenylacetylene from mesostilbene dibromide includes next reactions:
• Bromination of stilbene-it is the reaction of electrophilic adition and bromonium ion is formed as intermedier (meso compound is the product).
• Bimolecular elimination-strong base is used in this reaction (takes away the H) and pi bond is formed.
The answer would be 12 hope this helped