Answer:
The correct answer is -
1. protein synthesis or central dogma
2. leads to changes in the structure by changing in the codes which results in a decrease or loss of function.
Explanation:
1, Protein is made from the information coded in DNA base sequences by the two process protein synthesis that is also called central dogma. The two-process involve in this are transcription involves encoding the information present in DNA by mRNA molecule that codes the information in complementary sequence to DNA. which is then moved out of the nucleus and perform the translation with help of tRNA and ribosome to code the amino acid with help of triplet codes present in mRNA. These amino acids chain are called proteins.
2. Mutations can lead to change in the base sequences or deletion of the base which affects the structure of the protein and also leads to changes in an encoded protein or to a decrease or complete loss in its function or expression. Mutation can damage the cell or organism as it affects the gene expression of all cells of organisms.
It is transplanted routinely to treat a variety of blood and bone marrow diseases, blood cancers, and immune disorders. More recently, stem cells from the blood stream (called peripheral blood stem cells) and umbilical cord stem cells have been used to treat some of the same blood-based diseases
Urinary obstruction, Neurogenic bladder, Catheterization, Pregnancy and diabetes
