I believe that the <span>pervasive theme in Northern Renaissance culture that is implicit in Albrecht Altdorfer's The Battle of Issus is humanist interest in ancient history and culture.
The painting depicts events of 333 BC battle between Alexander the Great and Darius III of Persia.
</span>
Answer:
False
Explanation:
Glycolysis is the breakdown of glucose by enzymes releasing energy and pyruvic acid.
Answer:
The main function of the RB protein is to inhibit the transition from the G1 to S phase. Its activity depends on its phosphorylation state: if RB is not phosphorylated (active state), it is bound to the transcription factor E2F, preventing its translocation to the nucleus and the activation of genes necessary for DNA synthesis; and if it is phosphorylated, by cyclin-CDK complexes, E2F is released and cell proliferation occurs.
Explanation:
Retinoblastoma (Rb) was the first tumor suppressor described and, as we know today, mutations in its structure determine a large number of cancers. Structurally, we speak of a large and multifunctional protein; which is organized in different domains. The activity of this protein is regulated, mainly, by phosphorylation at multiple sites described over the years and is involved in control mechanisms of the cell cycle, apoptosis and senescence.