Colchicine inhibits the formation of the microtubules or spindle fibers. Without the spindle fibers the chromosomes cannot move to the poles.
Explanation:
Spindles and microtubules are both important components of cellular division. The structures go hand in hand with each other and are necessary for cellular division to occur.
Spindle fibers form a protein structure that divides the genetic material in a cell. The spindle is necessary to equally divide the chromosomes in a parental cell into two daughter cells during mitosis and meiosis. During mitosis, the spindle fibers are called the mitotic spindle and it is called meiotic spindle during meiosis,
On one side of the grand canyon could be a squirrel with a birth defect witch reproduses with a squirrel with normal genes. But the birth defect is stronger than whatever trait that may be. so the litter of squirrels mostly have this trait. and the cycle contiues