In the short term, the voyages led to the destruction of the natives of the lands that Columbus found. Some of them were killed outright. Others were enslaved. Many died of diseases brought by the Europeans.
The two items common in Europe did the conquistadores introduce to the people of Mesoamerica and South America are horses and wagons. Thank you for posting your question. I hope that this answer helped you. Let me know if you need more help.
I would like to answer, but not enough info..
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