Question

Which event has to proceed all others during endochondral ossification?

Answer 1

Answer:

Hyaline cartilage model formation is the event that should proceed all others during endochondral ossification.

Explanation:

• The Greek root word for cartilage is ‘chondro’. Endochondral ossification is the systematic formation or replacement by bones to develop the growing skeleton from a growing cartilage.
• Mesenchymal cells are converted to chondroblasts to chondrocytes and then to a hyaline cartilage model. This leads to the development of long bones of both the axial (ribs) and the appendicular skeleton (limb bones).
• The sites of endochondral ossification are the physis, epiphysis, and cuboidal bones.
• The five main steps involved in endochondral ossification are –  

1. Bone collar formation
2. Cavitation
3. Periosteal bud invasion
4. Diaphysis elongation
5. Epiphiseal ossification