Linear fixed model is a statistical model that includes both fixed effects and random effects is known as a mixed model, mixed-effects model, or mixed error-component model. These models have applications in a wide range of fields in the physical, biological, and social sciences.
<h3>How do you perform a genome scan with a linear mixed model?</h3>
Mice genetic mapping provides a superb illustration of the value of population structure. The tiny number of founders (fancy mice) from whom laboratory mouse strains originated led to many population bottlenecks. The history of wild-derived strains differs from that of laboratory strains since they are not descended from fancy mice. In order to tackle relatedness between people and population structure issues brought on by varying ancestries, linear mixed models were devised. In order to account for population structure, known kinship, and unknowable relatedness, linear mixed models (LMMs) take genome-wide similarity between all pairings of individuals into consideration. By include kinship in the model, linear mixed models in mapping studies can successfully adjust for genetic relatedness between individuals in a population.
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The provided question lack the essential part which is required to answer the question, however the correct part is attached with with the question as image.
Answer:
From the provided punnett square it is clear that the genotype of parents are Rr for each. On this basis offspring which is maria that can be either RR, Rr, or rr. Maria have chances to get RR= 25%.
There can be no 100 surety of the phenotype of maria as there is 25% chances of rr and 75% of ability of tongue rolling.
to get Rr=50% and rr = 25%
Answer:
A predominance of pine trees
Explanation:
Usually pine trees become a target of fire and can overcome the soil that has been a exposed to fire. Hence, in a woodland that has been frequented by fire, there is growth of pine trees rather than other trees/plants.
Answer:
the northern hemisphere is in summer and the southern hemisphere is in winter
Explanation:
the northern hemisphere is tilted toward the sun and the southern hemisphere is tilted away
Answer:
You are interested in obtaining Staphylococcus aureus for a study investigating the prevalence of methicillin-resistant Staphylococcus aureus in the general population. You have received several samples and are ready to start your isolation procedures. Describe the personal protective equipment that would be needed and three different culturing techniques that can be used to obtain organisms to produce pure cultures. State if you use general or selective media and which specific media you would choose. How would you determine if the culture was contaminated? What is the first step you would take if you detected contamination?
Personal Protective equipment needed; No special precautions are necessary when working with methicillin-resistant staphylococcus aureus, staphylococcus aureus is a bio-safety level
Three different culturing media; to include;
- Etest Method
- Disc Diffusion
- Latex Agglutination.
Properly enriched selective media is used.
The most accurate method for identifying Merthicillin-resistant staphylococcus is to test for the presence of mecA gene by PCR.
The best specific media is latex agglutination test and oxacillin salt agar screen.
How to determine if the culture was contaminated;
It can be spotted by the turbidity of the growth medium or the floating branching mycelia, bacteria contamination can be detected under 10× microscope within few days of contamination.
Step to take if contamination is detected;
Biological contamination is a serious issue and being able to correctly identify different types of contamination is an essential first step in ensuring the safety of your culture.
Explanation:
The literature on methicillin susceptible testing is extensive, and often conflicting in recommendations regarding the most important method for routine use. this is partly because the various studies of phenotypic methods have included different strains, which may differ significantly in heterogeneity and behave differently under particular test condition.
