Diseases introduced by white settlers.
The main reason for the wipe-out of Native Americans was the threat of the diseases introduced by White Europeans. This ended up killing many Native Americans across different tribes, as they had no immunity to these diseases and had never dealt with these kinds of illnesses before. This was a rampant problem and attained the Native Americans quickly after the European settlers arrived.
What you are reading and think what is in the text so you can understand it better.
That it’s America’s destiny to control all the land from sea to sea
