"The Lend-Lease Act" is what represented a shift from the foreign policy that dominated American politics between the two world wars, since this Act meant the US was giving direct assistance to Britain during WWII, which was a drastic shift from the strict isolationism that had existed before.
Daniel Hale William openned the firat interracial staff hospital. He was the first one in performing an operation on a human heart. He succeded even when there were no blood transfusions, antibiotics or x-rays. He was able to change tactics if he saw that he needed to do that. For example, he was one of the first ones in using the catgun.