In biochemistry, aligand is a substance that forms a complex with a biomolecule to serve abiological purpose. In protein-ligandbinding, the ligand is usually a molecule which produces a signal by binding to a site on a target protein.
Receptor mediated endocytosis is an endocytotic mechanism in which specific molecules are ingested into the cell. The specificity results from a receptor-ligand interaction. Receptors on the plasma membrane of the target tissue will specifically bind to ligands on the outside of the cell. An endocytotic process occurs and the ligand is ingested.
A very well studied example of receptor mediated endocytosis involves the metabolism of cholesterol.
Answer:
Sun
Explanation:
Sun is the only star in our solar system, and planets orbit around it. Our solar system is the part of Milky way (located in one of the outer bands of the Milky way), and the Milky way is the part of the Universe (Universe is made up of billions of galaxies, and Milky way is one of those galaxies). Hence, in the given options, the Sun is the part of all of the other options given.
PZ120 is not considered to be an enhancer to transcription in the metallothionein 2a gene.
<h3>About metallothionein 2A.</h3>
Metallothionein-2 is a metallothionein protein that in humans is encoded by the MT2A gene.
In human it is expressed in;
- right lobe of liver
- olfactory bulb
- left uterine tube
- external globus pallidus
- right lobe of thyroid gland
- upper lobe of left lung
- Region I of hippocampus proper
- right lung
- left lobe of thyroid gland
It's molecular function are;
- Protein ion binding
- Zinc ion binding
- Metal ion binding
It helps in various biological processes;
- response to metal ion
- cellular response to interleukin-3
- cellular response to erythropoietin
- negative regulation of growth
- cellular response to zinc ion
- interferon-gamma-mediated signaling pathway
- cellular copper ion homeostasis
- cellular zinc ion homeostasis
- detoxification of copper ion
- cellular response to cadmium ion
- cellular response to copper ion
- nitric oxide mediated signal transduction
- response to bacterium
To learn more about Metallothionein 2a,
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Most people affected would live in China: 43 million or around 20 percent. At 32 million and 27 million affected people, Bangladesh and India would also be hit hard, as would be Vietnam, Indonesia, Thailand, the Philippines and Japan. In Europe, the Netherlands would theoretically be the most affected.
