Lets eliminate
A. organ transplant:
this was debated maybe 200 years ago (give or tak) and is no longer an issue
B. genetic engineerign
this is kind of debated becuase some scientists are trying to make life and that has to do with ethics because they would be playing god
C. space exploration
not debatable
D. prosthetics
we already have this and tis i not debatable
answer is B
The development that probably hurt it is the reduction of open range herding. In history, people could just let their cattle roam freely and find food since the plains were huge and nobody lived in them. Nowadays, this can be problematic because there are more and more people and settlements and roads with cars so free range herding has been drastically reduced which cost the herders a lot.