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3 years ago

What advantage might chromosome banding patterns have in the analysis and diagnosis of chromosomal problems or abnormalities?

1 answer:

4 0

<span> Chromosomal banding pattern is the pattern of colors formed when the chromosome is exposed to certain specific dyes.

These dyes do a color reaction with a special repetitive sequence of base pairs.

When the normal pattern is not obtained
there may be two reasons
1. Chromosomal injury
2. Chromosomal aberration.

In injury certain part is either deleted or shifted to somewhere else

in aberration chromosome is normal but its sequence is got changed.

So its certain that is has got great diagnostic value.
But it fails
in case of point mutation or certain others.

This banding pattern is also helpful in preliminary diagnosis of a suspect in any crime but most of the judiciaries do not assure of its results. </span>

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3 years ago

A biologist at World University used Procedure IV to conduct an additional study and found the sequence following below. Using y

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Answer:

Valine-Leucine-Proline-Lysine-Histidine

Explanation:

The central dogma of biology is the process by which DNA is used to synthesize RNA and subsequently amino acid sequence (PROTEIN). The processes of transcription and translation is used in gene expression. Transcription is the process whereby the information encoded in a DNA molecule is used to synthesize a mRNA molecule. Transcription is catalyzed by RNA polymerase enzyme, which uses complementary base pairing rule i.e Adenine(A)-Thymine(T), Guanine(G)-Cytosine(C) pairing.

N.B: Thymine is replaced by Uracil in the mRNA

For the above DNA sequence: CAC GAC GGA TTC GTA, the mRNA sequence will be: GUG CUG CCU AAG CAU

Translation is the second process of gene expression which involves the synthesis of an amino acid sequence from an mRNA molecule. The mRNA is read in a group of three nucleotides called CODON. Each codon specifies an amino acid (see attached image for genetic code)

Based on the attached genetic code, an mRNA sequence: GUG CUG CCU AAG CAU will encode an amino acid sequence: Valine(Val) - Leucine (Leu) -Proline (Pro) -Lysine (Lys) - Histidine (His).

GUG specifies Valine amino acid

CUG specifies Leucine amino acid

CCU specifies Proline amino acid

AAG specifies Lysine amino acid

CAU specifies Histidine amino acid

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Explanation:

hope this helps

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