Answer:
DNA vaccines consist of DNA vectors or plasmids (small double-stranded DNA rings originally derived from bacteria, but unable to cause infection) into which the genes encoding one or more immunizing proteins of the infectious agent have been inserted causing the disease to be prevented.
Explanation:
Vectors are the functional unit of naked DNA vaccines. Genes that encode the proteins of interest and are of bacterial origin are inserted into these vectors. Bacterial plasmids are circular DNA molecules that self-replicate extrachromosomally in bacteria. The genes encoded in these plasmids are under the control of promoters, almost always of viral origin. When a plasmid is introduced into the cell it translocates to the nucleus, where transcription of the transgene begins; the transcripts are then taken to the cytoplasm and translated there. The newly synthesized proteins are degraded in the proteasome to 8-10 amino acid peptides, which are transported to the endoplasmic reticulum. Peptides of high affinity with their respective MHC I molecule stabilize and enter the secretory pathway, thus reaching the cell surface, where they are coupled with the T-lymphocyte receptor (TcR) present on the surface of T lymphocytes cytotoxic drugs (CD8 +) to induce their activation.
Answer:
separate or unzip the two strands of the double helix.
Explanation:
Mark as brainslist. Hope this helps.
I’m not for sure but I believe it is A
Answer: In an ionic bond the valence electrons are transferred from the metal only to the neighboring nonmetal, but in metallic bonding the valence electrons of each atom/ion are free to move or float around within the entire metal solid.
Explanation:
