When counting the total population of a state, all free white men and women would be counted, but only 3/5ths of the African-American slave population would be counted towards the total.
Answer: 2
Explanation: The South was less industrialized than the North, the south grew more plants/crops, the north had favored a more federal government than the south, and the south had relied on slaves a lot. So I'd say number 2.
Hypothermia is used widely during open heart surgery due to its cytoprotective effects. In addition to this, other mechanisms of therapeutic hypothermia include suppression of free radicals, inhibition of destructive enzymatic reactions, reduction in metabolic requirements in low-flow regions, and inhibition of the biosynthesis, release, and uptake of excitatory neurotransmitters. Through these mechanisms, hypothermia provides a favorable balance between oxygen supply and demand, slows the onset of ischemic depolarization, decreases the release of ischemic-induced intracellular calcium influx, and suppresses nitric oxide synthase activity.
Hypothermia is widely used in open cardiac surgery not only to protect against perioperative brain ischemia that could potentially develop, but also the myocardium.
All of those are a part of Great Britain
