OBJECTIVES: To analyze the occurrence and types of neoplasias that have developed in patients submitted to orthotopic heart transplantation in the Cardiac Transplantation Program of the Paulista School of Medicine, Federal University of São Paulo.
METHODS: The present study presents an observational analysis of 106 patients submitted to orthotopic heart transplantation from November 1986 to September 2002, who survived for more than 30 days after the procedure. The immunosuppressive regimen consisted of triple therapy with cyclosporin A, azathioprine and corticosteroid. Only two patients received, in addition to triple therapy, the addition of orthoclone OKT-3. The mean follow-up period was 61.4 months. (variation from two months to 192 months).
RESULTS: Twenty-three patients (21.3%) developed neoplasias, of which 56.5% had skin neoplasms, 30.1% had solid tumors and 13.4% had post-transplantation lymphoproliferative disease (PTLD). The mean interval between transplantation and the diagnosis of neoplasia was: skin - 54.9 months, solid tumors - 24.8 months and DLPT - 70.3 months.
CONCLUSIONS: The occurrence of malignant neoplasms was relatively common in the analyzed population. Skin cancer prevailed in relation to other neoplasms and solid tumors were more diagnosed than lymphoproliferative diseases in this series of patients.
I think it is adverb clause because of the word "hardly" which emphasises the ripple of the water
Answer:
The author has described the development of the justice system's understanding and treatment of juvenile offenders over time as pathetic. she opines that the understanding and treatment as unreasonable, inhumane and miserable, taking into account the evolution of the modern era and the current times of the human race
The feeling invoked by the author is to show the freedom of accepting of fate by the narrator.
Explanation:
The feelings described here are numerous in small amount of time. The feeling of the narrator is at first described to be strangely fearless.
This makes one think that there is something to fear which is why it has become fearless.
But then the author describes the feeling by the use of imagery and we understand that Phil is in fact drowning and these emotions are his understanding that he will now not survive at all.
There is no chance to survive so he accepts his fate and feels strangely free.
Pardon my french to us, is normally just used to apologize for using profanity.
I wish I could explain why, but I honestly have no idea.
Hope this helps though!
