<span>A drug used to treat CML, imatinib, binds to the active site of Abl kinase. Why does this drug work to treat this type of cancer?
</span><span>B) By binding to the active site, the drug prevents the ability of Abl kinase to bind to its substrate.
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Imatinib works against CML by binding close to the ATP binding site of bcr-abl. The binding results to the<span> locking in of the bcr-abl to a closed or self-inhibited conformation and inhibiting the enzyme activity of the protein </span><span>semi-competitively.</span>
A phenomenon, in the scientific context, is an observable event that can range from a seasonal hazard to a technological issue. For a scientist, a phenomenon is an observable event.
When a specimen is to be observed under the light microscope, scientists usually stain the specimens using different type of chemical stains depending on the type of specimen to be observed. Staining of specimen make the structures that are to be observed in the specimen very visible under the microscope, this make it easy for scientists to observe their structures.
3. Replication
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4. The cell's nucleus divides into two new nuclei; One copy of DNA is distributed into each daughter cell.
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5. anaphase
6. Prophase
7. Telophase
8. metaphase