*Sickle cell disease is a constitutional corpuscular hemolytic anemia related to an abnormal structure of the globin chain. It is an autosomal recessive disease, which means homozygosity is necessary to fully express the illness.
*It corresponds to the synthesis of an abnormal hemoglobin, HbS, which is different from normal Hb (HbA).
*The S allele (located in the chromosome 11), responsible for the anomaly, is especially widespread in the African continent, it is also found in other regions of the Mediterranean.
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*Mutation GAG to GTG leading to the substitution Glutamine by a valine in position 6 of the chain of the globine.</span>
Brain structure that controls the autonomic nervous system is the hypothalamus of the brain. It is located on lower part of the top end of the brain stem. The hypothalamus specifically important for maintaining homeostasis, the proper balance of the body’s internal environment such as body temperature, blood sugar, breathing. Thus, the hypothalamus maintains homeostasis by controlling the autonomic nervous system.
the cell structure cytoplasm serves the state of function in both eukaryotic and prokaryotic cells.
