The answer would be D. Contain cytoplasm.
bacteria(prokaryotic cells) have a cell membrane, cytoplasm, DNA, ribosomes but lack all membrane bound organelles that eukaryotic cells have.
Answer:
by designing a drug with steric effects on BCR-ABL1
Explanation:
Chronic myeloid leukemia (CML) is a type of cancer that affects the bone marrow and blood cells. CML is characterized by the formation of the Philadelphia chromosome, a product of a reciprocal translocation between chromosomes 9 and 22. As a consequence of this translocation, an oncoprotein tyrosine kinase called BCR-ABL1 is formed. This protein (BCR-ABL1) is responsible for 95% of all CMLs. In this case, it is possible to inhibit BCR-ABL1 (and thus inhibit CML cell proliferation) by using a kinase inhibitor. Kinase inhibitors are drugs that inhibit kinase function by preferentially binding to the inactive conformation of the target enzyme. These proteins are used to treat cancer by blocking a functional site on the kinase, thereby inhibiting its function. Moreover, it is known that steric effects alter the mode and rate by which a drug interacts with a given target. In this case, a small molecule with steric effects on BCR-ABL1, i.e., capable of altering the shape (conformation) and reactivity of BCR-ABL1, might also be used to selectively inhibit BCR-ABL1.
-Headaches, which may be severe and worsen with activity or in the early morning.
-Seizures. People may experience different types of seizures. Certain drugs can help prevent or control them.
-Personality or memory changes.
-Nausea or vomiting.
-Fatigue.
-Drowsiness.
-Sleep problems.
-Memory problems.
