Answer:
the pathway will be under-expressed.
- the alpha subunit helps to bind with either GDP or GTP. when the α subunit is bound with GDP, it will be bound to β and γ subunits and thus forms an inactive state for G-protein.
- when the alpha subunit binds with the GTP, it becomes activated and dissociates β and γ subunits.
if G-protein Coupled Receptor is unable from dissociating β and γ subunits, then the pathway will go under expression.
The chemical qualities of the alpha subunit allow it to bind easily to one of two guanine subunits, GDP or GTP. The protein thus has two functional formations. When GDP is bound to the alpha subunit, the alpha subunit remains bound to the beta-gamma subunit to form an inactive trimeric protein.
G-proteins, cAMP, and Ion Channel Opening. The alpha subunit activates adenylate cyclase, in purple, and loses GTP. Adenylate cyclase converts ATP to cyclic AMP, which then activates Protein Kinase, shown in blue. Protein Kinase phosphorylates an ion channel, letting sodium ions rush into the cell.
As a result of the ligand binding to its site on the G-protein-linked receptor, A) the G-protein changes conformation and GTP replaces the GDP on the alpha subunit. ... Inactivation of the alpha subunit occurs when its own phosphorylase activity removes a phosphate from the GTP.
B is your answer. God Bless hope this helps
DNA is the molecule that contains the genetic information that is transmitted hereditary and controls the cellular functioning
Answer:
The increase in the human population and waste it produces, deforestation , peat bog destruction and global warming are all reducing biodiversity
Explanation:
Answer:
The solute is powdered drink mix
Explanation:
The solute is powdered drink mix is solute because solute is any substance that dissolves in a solvent while solvent is the substance that dissolve solute or the dissolving medium. When solute dissolve in solvent it is called solution.
Solution is an homogeneous mixture of substance which comprises of solute that dissolve in solvent.
